From my experience, life is far more enjoyable when I don't play TF2 during college. I've gone 2 semesters without any TF2, one when I just MGE'd and one where I played on a team (Explosion), and the amount of fun I had definitely went from without>casual>competitive.
During the times I didn't play any TF2 I obviously had far more time to hang out with my friends and meet people, and so... I hung out with my friends and met people. My GPA was also higher during these times and I just felt I enjoyed life more.
Then again, having stayed on campus, playing TF2 was stressful for me, as people who have played on a team with me know; there is always like 6-10 people in my room. So in the end it just wasn't worth it for me.
If you go to a community college or if you live far off campus/don't know anyone at your school I would recommend playing games in order to pass by the downtime, but if you live on campus/have friends at school, I think you'll definitely have more fun if you uninstall the game until summer.